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Table 3 Additional genetic variants associated with cocaine-associated agranulocytosis

From: Genetic determinants of cocaine-associated agranulocytosis

SNP Gene Chr Alleles Type Allele frequency (%)
Cases Controls Odds ratio (95% CI) P value Corrected P value
rs10885531 ADRB1 10 G/A Intragenic 0 53.8 0.06 (0.007–0.46) 9.09 × 10−6 0.043
rs7193955 ABCC12 16 A/G Nonsynonymous 75 23.1 10 (2.7–36.8) 1.00 × 10−4 0.47
rs2279357 CYP11A1 15 G/A Intronic 75 28.8 7.4 (2.1–26.6) 7.29 × 10−4 1
  1. SNP single nucleotide polymorphism, CI confidence intervals, Chr chromosome.
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