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Table 3 Additional genetic variants associated with cocaine-associated agranulocytosis

From: Genetic determinants of cocaine-associated agranulocytosis

SNP

Gene

Chr

Alleles

Type

Allele frequency (%)

Cases

Controls

Odds ratio (95% CI)

P value

Corrected P value

rs10885531

ADRB1

10

G/A

Intragenic

0

53.8

0.06 (0.007–0.46)

9.09 × 10−6

0.043

rs7193955

ABCC12

16

A/G

Nonsynonymous

75

23.1

10 (2.7–36.8)

1.00 × 10−4

0.47

rs2279357

CYP11A1

15

G/A

Intronic

75

28.8

7.4 (2.1–26.6)

7.29 × 10−4

1

  1. SNP single nucleotide polymorphism, CI confidence intervals, Chr chromosome.