From: Genetic determinants of cocaine-associated agranulocytosis
SNP | Gene | Chr | Alleles | Type | Allele frequency (%) | ||||
---|---|---|---|---|---|---|---|---|---|
Cases | Controls | Odds ratio (95% CI) | P value | Corrected P value | |||||
rs10885531 | ADRB1 | 10 | G/A | Intragenic | 0 | 53.8 | 0.06 (0.007–0.46) | 9.09 × 10−6 | 0.043 |
rs7193955 | ABCC12 | 16 | A/G | Nonsynonymous | 75 | 23.1 | 10 (2.7–36.8) | 1.00 × 10−4 | 0.47 |
rs2279357 | CYP11A1 | 15 | G/A | Intronic | 75 | 28.8 | 7.4 (2.1–26.6) | 7.29 × 10−4 | 1 |