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Table 2 NAFLD activity scoring system according to Kleiner et al

From: Prevalence of non-alcoholic fatty liver disease in four different weight related patient groups: association with small bowel length and risk factors

NAFLD Activity Score (NAS) (0–8)
 Sum of scores for steatosis, lobular inflammation and hepatocellular ballooning
 ≥5 probable or definite NASH
 3–4 uncertain NASH
 ≤2 no NASH
Steatosis (0–3) Lobular inflammation (0–3) Hepatocyte ballooning (0–2)
 0: 5% hepatocytes involved  0: none  0: none
 1: 5–33% of hepatocytes involved  1: <2 foci per × 200 field  1: few ballooned cells
 2: 33–66% hepatocytes involved  2: 2–4 foci per × 200 field  2: many cells/prominent ballooning
 3: >66% hepatocytes involved  3: >4 foci per × 200 field  
Correlation between total NAFLD activity scores and an overall histological diagnosis of steatohepatitis
 NAFLD activity score and histological diagnosis of steatohepatitis
 ≥5 probable or definite NASH
 3–4 uncertain NASH
 ≤2 no NASH