Evidence that histone H1 is dispensable for proper meiotic recombination in budding yeast

Table 2 Crossover interference analysis by NPD ratio in HHO1 ⁺ and hho1Δ cells

Interval	Strain	NPD Ratio (NPD_o/NPD_e)	P	I
URA3-LEU2	HHO1 ⁺	0.31 (3/9.7)	0.0104	Yes
URA3-LEU2	hho1Δ	0.30 (3/10.0)	0.0082	Yes
LEU2-LYS2	HHO1 ⁺	0.24 (2/8.3)	0.0100	Yes
LEU2-LYS2	hho1Δ	0.11 (1/9.0)	0.0017	Yes
ADE2-HIS3	HHO1 ⁺	0.43 (9/20.7)	0.0005	Yes
ADE2-HIS3	hho1Δ	0.56 (12/21.4)	0.0062	Yes

NPD events observed (NPD_o) and those expected in the absence of crossover interference (NPD_e) were compared. P < 0.05, based on a Chi square test, is considered statistically significant evidence of crossover interference (I).