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Table 3 Crossover interference analysis by coefficient of coincidence (COC) in HHO1 + and hho1Δ cells

From: Evidence that histone H1 is dispensable for proper meiotic recombination in budding yeast

Adjacent Intervals Strain COC (DCOo/DCOe) P I
URA3-LEU2-LYS2 HHO1 + 0.70 (44/62.4) 0.0088 Yes
hho1Δ 0.72 (48/66.5) 0.0105 Yes
LEU2-LYS2-ADE2 HHO1 + 0.51 (20/39.2) 0.0012 Yes
hho1Δ 0.56 (19/33.7) 0.0085 Yes
LYS2-ADE2-HIS3 HHO1 + 0.80 (46/57.7) 0.0930 No
hho1Δ 0.90 (43/47.6) 0.5093 No
  1. The number of tetrads exhibiting crossover events (TT or NPD) in both of the indicated adjacent intervals (DCOo) was compared with the number expected in the absence of crossover interference (DCOe). P < 0.05, based on a binomial probabilities test, is considered statistically significant evidence of crossover interference (I).