Evidence that histone H1 is dispensable for proper meiotic recombination in budding yeast

BMC Research Notes

Table 3 Crossover interference analysis by coefficient of coincidence (COC) in HHO1 ⁺ and hho1Δ cells

Adjacent Intervals	Strain	COC (DCO_o/DCO_e)	P	I
URA3-LEU2-LYS2	HHO1 ⁺	0.70 (44/62.4)	0.0088	Yes
URA3-LEU2-LYS2	hho1Δ	0.72 (48/66.5)	0.0105	Yes
LEU2-LYS2-ADE2	HHO1 ⁺	0.51 (20/39.2)	0.0012	Yes
LEU2-LYS2-ADE2	hho1Δ	0.56 (19/33.7)	0.0085	Yes
LYS2-ADE2-HIS3	HHO1 ⁺	0.80 (46/57.7)	0.0930	No
LYS2-ADE2-HIS3	hho1Δ	0.90 (43/47.6)	0.5093	No

The number of tetrads exhibiting crossover events (TT or NPD) in both of the indicated adjacent intervals (DCO_o) was compared with the number expected in the absence of crossover interference (DCO_e). P < 0.05, based on a binomial probabilities test, is considered statistically significant evidence of crossover interference (I).

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