Table 1 Mean ± SD of body weight, total liver weight, liver enzymes, albumin, renal function and metabolic parameters in the different study groups
Control | PEG-IFN Only | PEG-IFN & Ribavirin | Ribavirin Only | |
|---|---|---|---|---|
Body weight (g) | 221.57 ± 20.01 | 231.97 ± 23.01 | 218.42 ± 13.64 | 230.1 ± 22.2 |
Liver weight (g) | 11.04 ± 1.26 | 10.54 ± 1.52 | 10.27 ± 0.44 | 10.23 ± 1.5 |
ALT (U/l) | 60.4 ± 16.2 | 68.8 ± 18.6 | 53.9 ± 19 | 64.1 ± 11.5 |
AST (U/l) | 92.4 ± 24.2 | 129.8 ± 46.7 | 119 ± 21.6 | 133 ± 49.8 |
Albumin (g/dl) | 3.4 ± 0.4 | 3.3 ± 0.5 | 3.7 ± 0.3 | 3.5 ± 0.5 |
Creatinine (mg/dl) | 0.22 ± 0.03 | 0.2 ± 0.06 | 0.2 ± 0.03 | 0.19 ± 0.03 |
Urea (mg/dl) | 47.6 ± 5.1 | 52.3 ± 4 | 56.6 ± 9.5 | 47.3 ± 5.8 |
BUN (mg/dl) | 22.2 ± 2.4 | 24.4 ± 1.9 | 26.3 ± 4.4 | 22 ± 2.7 |
Glucose (mg/dl) | 110.7 ± 12.7 | 118.9 ± 23.1 | 112.6 ± 12.7 | 114.5 ± 16.1 |
Triglycerides (mg/dl) | 77.3 ± 20.3 | 68.3 ± 13.9 | 63.2 ± 9.5 | 85 ± 28.5 |
Cholesterol (mg/dl) | 45 ± 7.2 | 58.5 ± 12.4 | 62.2 ± 14.5 | 64.8 ± 9.7 |
HDL-C (g/dl) | 36.2 ± 9.2 | 44.3 ± 1.2 | 52.8 ± 7.8 | 53.1 ± 7.7 |
LDL-C (g/dl) | 6.6 ± 1.7 | 8.14 ± 2.33 | 7.1 ± 2.5 | 6.3 ± 1.55 |