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Table 2 Broad spectrum antimicrobial screening of extracts of selected plants

From: Antimicrobial activity of customary medicinal plants of the Yaegl Aboriginal community of northern New South Wales, Australia: a preliminary study

MicrobeA: CA CMRSA MDRSA SP
Plant ExtB Disc diffusionC Average (range) MTT MICD Median (range) Disc diffusionC Average (range) MTT MICD Median (range) Disc diffusionC Average (range) MTT MICD Median (range) Disc diffusionC Average (range) MTT MICD Median (range)
Corymbia intermedia (R.T. Baker) K.D. Hill & L.A.S. Johnson (NSW 792670) H2O 6.5 (6–8) 500 (250–500) 3 (2.5–3) 500 (250–500) 3 (2–4) 500 na na
EtOH 2 (0–6.5) 500 (250–500) 2.5 (2–5.5) 375 (250–500) 2.5 (1.5–4) 250 (250–500) na 250 (125–>1,000)
Lophostemon suaveolens (Sol. ex Gaertn.) Peter G. Wilson & J.T. Waterh (MQ 73008908) H2O 6 (5.5–6) 1,000 (500–1,000) 2.5 (2–3) 1,000 (500–1,000) 2.5 (2–3) 1,000 (250–1,000) na na
EtOH 6.5 (6–7) 125 (31–125) 3.5 (3–4.5) 63 (63–125) 3.5 (3–5) 125 (63–250) na 125 (16–>1,000)
Syncarpia glomulifera subsp. glomulifera (Sm.) Nied. (MQ 73009066) H2O 6.5 (5.5–7.5) 500 (250–1,000) 3 (3–4) 375 (250–500) 2.5 (2–3) 250 (31–500) na na
EtOH 5.5 (5–6) 31 (16–1,000) 5 (2.5–5) 31 (16–1,000) 3.5 (2–5) 31 (16–>1,000) 3 (2–4.5) 31 (31–>1,000)
Antibiotic control   17a 2.8b 3c 1.5c 2c 1.6c 8d 0.02d
  1. Antibiotic controls: afluconazole, bmiconazole ,cvancomycin, dpenicillin.
  2. na no activity detected.
  3. ACA: Candida albicans (clinical isolate); CMRSA: S. aureus (ATCC BAA 1026); MDRSA: S. aureus (multidrug resistant clinical isolate); SP: Streptococcus pyogenes (Group A—clinical isolate).
  4. BExtraction method used: H2O, traditional prep; EtOH, 80% aqueous ethanol.
  5. CValues given are inhibition in mm from the edge of the disc; average of four replicates (plant extracts tested at 1 mg/disc and antibiotic controls tested at 2 µg/disc).
  6. DMIC noted as µg/mL, based on the last dilution of extract not to exhibit yellow–blue colour change in MTT assay; values given are median (range) of 4 replicates.