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Table 2 Pooled intervention effects on LDL-C and QALYs after 12 months

From: An economic evaluation alongside a randomized controlled trial evaluating an individually tailored lifestyle intervention compared with usual care in people with Familial Hypercholesterolemia

Pooled effects (pooled mean (SEM)) Control group N = 159 Intervention group N = 181 Intervention versus control
Baseline Follow-up Baseline Follow-up Mean difference (95% CI)
LDL-C (mmol/l) 3.7 (0.1) 3.6 (0.1) 3.7 (0.1) 3.5 (0.1) −0.14 (−0.34 to 0.07)
QALYs achieved 0.9 (0.01) 0.9 (0.01) −0.002 (−0.02 to 0.01)
  1. Effects were calculated after multiple imputation and with adjustment for baseline values.
  2. LDL-C low-density lipoprotein cholesterol, QALY quality adjusted life year, SEM standard error of the mean; the maximum QALY that can be achieved in one year is 1 unit.