An economic evaluation alongside a randomized controlled trial evaluating an individually tailored lifestyle intervention compared with usual care in people with Familial Hypercholesterolemia

Table 2 Pooled intervention effects on LDL-C and QALYs after 12 months

Pooled effects (pooled mean (SEM))	Control group N = 159		Intervention group N = 181		Intervention versus control
Pooled effects (pooled mean (SEM))	Baseline	Follow-up	Baseline	Follow-up	Mean difference (95% CI)
LDL-C (mmol/l)	3.7 (0.1)	3.6 (0.1)	3.7 (0.1)	3.5 (0.1)	−0.14 (−0.34 to 0.07)
QALYs achieved	–	0.9 (0.01)	–	0.9 (0.01)	−0.002 (−0.02 to 0.01)

Effects were calculated after multiple imputation and with adjustment for baseline values.
LDL-C low-density lipoprotein cholesterol, QALY quality adjusted life year, SEM standard error of the mean; the maximum QALY that can be achieved in one year is 1 unit.

ISSN: 1756-0500