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Table 5 Results for cost-effectiveness and cost-utility analyses

From: An economic evaluation alongside a randomized controlled trial evaluating an individually tailored lifestyle intervention compared with usual care in people with Familial Hypercholesterolemia

 

Sample size

Cost difference in Euros (95% CI)

Effect difference (95% CI)

ICER

Distribution cost-effectivess plane (%NE/SE/SW/NW)

I

C

 

Main analysis (CEA1)

181

159

LDL-C

−237 (−1,386 to 130)

−0.14 (−0.34 to 0.07)

1,729

22.5/68.5/7.1/1.9

181

159

QALY

−237 (−1,386 to 130)

−0.002 (−0.02 to 0.01)

145,899

9.7/30.9/44.2/15.2

Complete case analysis (CEA2)

118

100

LDL-C

−364 (−2,030 to 238)

−0.14 (−0.37 to 0.08)

2,012

4.6/8.0/55.7/31.7

157

136

QALY

−301 (−1,680 to 109)

−0.003 (−0.03 to 0.03)

100,347

6.5/25.4/52.5/15.6

Intervention costs as in RCT (CEA3)

181

159

LDL-C

−88 (−1,248 to 277)

−0.14 (−0.34 to 0.07)

645

39.4/51.6/5.5/3.6

181

159

QALY

−88 (−1,248 to 277)

−0.002 (−0.02 to 0.01)

54,426

17.1/23.4/33.8/25.7

Hospital admission costs excluded (CEA4)

181

159

LDL-C

94 (−6 to 193)

−0.14 (−0.34 to 0.07)

−690

88.5/2.4/0.5/8.5

181

159

QALY

94 (−6 to 193)

−0.002 (−0.02 to 0.01)

−33,676

38.9/1.2/1.7/58.2