Genomic context of the CRISPR/Cas system in diverse strains of Klebsiella pneumoniae.
a Genomic context of cas operon. Enzymes related to bacterial metabolism and some antibiotic resistance genes are located in the vicinity of cas operon. b CRISPR/Cas organization. The cas operon consists of eight genes and the CRISPR sequences are located downstream from cas2 and upstream from cas3 in those genomes containing two CRISPR arrays.