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Table 4 Minimum inhibitory concentrations of erythromycin and clindamycin resistant isolates, D-shape and screened genes (n = 29)

From: Antibiotic resistance of Streptococcus agalactiae isolated from pregnant women in Garankuwa, South Africa

No

MIC (µg/ml)

D-shape

MLS

Genes

Erythromycin

Clindamycin

1

1 (R)

0.50 (I)

Negative

cMLSB

ermB

2

3 (R)

0.75 (I)

Negative

cMLSB

linB + ermB

3

0.75 (I)

0.75 (I)

Negative

cMLSB

linB + ermB

4

0.50 (I)

0.047 (S)

Negative

M phenotype

mefA

5

0.75 (I)

1 (R)

Negative

cMLSB

ermB

6

4 (R)

0.50 (I)

Negative

cMLSB

ermB

7

1 (R)

0.38 (I)

Negative

cMLSB

ermB

8

0.75 (I)

1 (R)

Negative

cMLSB

ermB

9

0.75 (I)

4 (R)

Negative

cMLSB

linB + ermB

10

4 (R)

7 (R)

Negative

cMLSB

ermB

11

2 (R)

0.047 (S)

Positive

iMLSB

ermTR

12

1.5 (R)

0.016 (S)

Positive

iMLSB

ermB

13

0.75 (I)

0.50 (I)

Negative

cMLSB

linB + ermB

14

8 (R)

0.38 (I)

Negative

cMLSB

ermB

15

0.25 (S)

2 (R)

Negative

L phenotype

linB + ermB

16

8 (R)

1 (R)

Negative

cMLSB

linB + ermB

17

0.75 (I)

1 (R)

Negative

cMLSB

ermB

18

3 (R)

0.38 (I)

Negative

cMLSB

ermB

19

1 (R)

0.38 (I)

Negative

cMLSB

ermB

20

1.5 (R)

0.25 (S)

Positive

iMLSB

ermB

21

0.25 (S)

1 (R)

Negative

L phenotype

linB + ermB

22

3 (R)

0.047 (S)

Positive

iMLSB

ermB

23

0.50 (I)

0.75 (I)

Negative

cMLSB

linB + ermB

24

2 (R)

8 (R)

Negative

cMLSB

ermB

25

0.75 (I)

0.50 (I)

Negative

cMLSB

linB + ermB

26

0.75 (I)

0.094 (S)

Negative

M phenotype

ermB

27

4 (R)

0.023 (S)

Positive

iMLSB

ermB

28

0.50 (I)

1 (R)

Negative

cMLSB

linB + ermB

29

0.75 (I)

0.50 (I)

Negative

cMLSB

linB + ermB

  1. S susceptible, R resistant, I intermediate, cMLS B MLSB-constitutive methylation [erythro (R), clinda (R)], iMLS B MLSB-inducible methylation [erythro (R), clinda (S) with blunting], M-phenotype efflux pump mechanism [erythro (R), clinda (S) without blunting], L-phenotype erythro (S), clinda (R)