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Table 3 Characteristics of Tg, TSH, fT4 and fT3 of different iodine status in primary school age children (n = 155) of Tehrathum and Morang districts

From: Urinary iodine excretion and thyroid function status in school age children of hilly and plain regions of Eastern Nepal

UIE category

Tga (µg/L)

fT3 (pmol/L)

fT4 (pmol/L)

TSHa (mIU/L)

Severe ID (n = 11)

 Mean

32.6

4.3

15.3

5.8

 SD

38.2

1.1

3.8

2.6

 Median

18.1

3.8

14.1

6.7

 IQR

12.8; 29.0

3.5; 5.7

12.9; 18.1

3.6; 7.5

Moderate ID (n = 14)

 Mean

39.5

4.4

16.2

4.1

 SD

59.3

1.1

3.5

2.9

 Median

21.0

4.0

17.0

3.3

 IQR

12.5; 35.9

3.7; 4.5

14.2; 19.4

2.1; 5.9

Mild ID (n = 29)

 Mean

25.5

4.3

16.8

4.7

 SD

16.0

1.1

4.3

2.2

 Median

22.7

4.3

16.3

4.1

 IQR

13.2; 31.1

3.2; 4.5

12.9; 19.4

3.5; 5.8

Adequate iodine nutrition (n = 126)

 Mean

15.3

4.1

17.2

3.8

 SD

9.8

1.2

4.6

2.0

 Median

13.7

4.0

16.6

3.5

 IQR

9.1; 18.7

3.4; 4.9

12.9; 20.6

2.2; 5.1

Above requirements (n = 147)

 Mean

18.6

3.8

16.4

5.3

 SD

14.4

1.1

4.2

6.4

 Median

15.2

3.6

15.6

3.7

 IQR

8.1; 25.1

3.1; 19.4

19.4; 12.9

2.3; 5.0

Excessive (n = 313)

 Mean

17.2

4.1

16.3

4.3

 SD

18.1

1.1

3.9

3.9

 Median

10.9

4.1

15.9

3.2

 IQR

6.5; 22.8

3.4; 4.9

12.9; 19.4

2.4; 5.5

  1. One way ANOVA test shows significant difference (p = 0.016) between Tg and UIE category. Post hoc analysis was carried out for Tg, fT3, fT4 and TSH by UIE categories separately. No statistically significant difference observed for other parameters (fT3, fT4 and TSH) with UIE category
  2. Level of significance: * p < 0.05
  3. ID iodine deficiency, Tg serum thyroglobulin, fT3 free triiodothyronine, fT4 free thyroxine, TSH thyroid stimulating hormone
  4. aNon-normally distributed variables were log transformed