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Table 3 Characteristics of Tg, TSH, fT4 and fT3 of different iodine status in primary school age children (n = 155) of Tehrathum and Morang districts

From: Urinary iodine excretion and thyroid function status in school age children of hilly and plain regions of Eastern Nepal

UIE category Tga (µg/L) fT3 (pmol/L) fT4 (pmol/L) TSHa (mIU/L)
Severe ID (n = 11)
 Mean 32.6 4.3 15.3 5.8
 SD 38.2 1.1 3.8 2.6
 Median 18.1 3.8 14.1 6.7
 IQR 12.8; 29.0 3.5; 5.7 12.9; 18.1 3.6; 7.5
Moderate ID (n = 14)
 Mean 39.5 4.4 16.2 4.1
 SD 59.3 1.1 3.5 2.9
 Median 21.0 4.0 17.0 3.3
 IQR 12.5; 35.9 3.7; 4.5 14.2; 19.4 2.1; 5.9
Mild ID (n = 29)
 Mean 25.5 4.3 16.8 4.7
 SD 16.0 1.1 4.3 2.2
 Median 22.7 4.3 16.3 4.1
 IQR 13.2; 31.1 3.2; 4.5 12.9; 19.4 3.5; 5.8
Adequate iodine nutrition (n = 126)
 Mean 15.3 4.1 17.2 3.8
 SD 9.8 1.2 4.6 2.0
 Median 13.7 4.0 16.6 3.5
 IQR 9.1; 18.7 3.4; 4.9 12.9; 20.6 2.2; 5.1
Above requirements (n = 147)
 Mean 18.6 3.8 16.4 5.3
 SD 14.4 1.1 4.2 6.4
 Median 15.2 3.6 15.6 3.7
 IQR 8.1; 25.1 3.1; 19.4 19.4; 12.9 2.3; 5.0
Excessive (n = 313)
 Mean 17.2 4.1 16.3 4.3
 SD 18.1 1.1 3.9 3.9
 Median 10.9 4.1 15.9 3.2
 IQR 6.5; 22.8 3.4; 4.9 12.9; 19.4 2.4; 5.5
  1. One way ANOVA test shows significant difference (p = 0.016) between Tg and UIE category. Post hoc analysis was carried out for Tg, fT3, fT4 and TSH by UIE categories separately. No statistically significant difference observed for other parameters (fT3, fT4 and TSH) with UIE category
  2. Level of significance: * p < 0.05
  3. ID iodine deficiency, Tg serum thyroglobulin, fT3 free triiodothyronine, fT4 free thyroxine, TSH thyroid stimulating hormone
  4. aNon-normally distributed variables were log transformed