Fig. 1
From: Challenges in exome analysis by LifeScope and its alternative computational pipelines
Schema comprising an investigated workflow of exome analysis by LifeScope and the alternative pipeline. This schema represents exome’s computational pipeline steps that were applied in the study. The LifeScope’s pipeline includes proprietary programs to perform alignment and variant calling. Alternatively we applied another four approaches based on combinations of LifeScope, SHRiMP, MAQ, BFAST mapping programs and GATK modules for variant calling, using the same exomes as with Lifescope program