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Table 2 Sample size necessary to demonstrate a significant difference in hazard ratio (HR)

From: Biopsy vs. extensive resection for first recurrence of glioblastoma: is a prospective clinical trial warranted?

Power (%)

HR

1.2

1.3

2.0

70

742

359

51

80

945

456

65

90

1264

611

87.5

  1. Assumes two-sided significance (alpha) of 5 %
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BMC Research Notes

ISSN: 1756-0500

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