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Table 4 Mean area under curve of Chi8 and GBOOST on simulated GWAS of 800 subjects

From: Chi8: a GPU program for detecting significant interacting SNPs with the Chi-square 8-df test

Allele freq.

0.1

0.2

0.4

Model 1

 Chi8

0.4

0.41

0.32

 GBOOST

0.1

0.1

0.07

Model 2

 Chi8

0.68

0.88

0.85

 GBOOST

0.08

0.64

0.68

Model 3

 Chi8

0.45

0.54

0.81

 GBOOST

0.09

0.14

0.62

Model 4

 Chi8

0.64

0.84

0.86

 GBOOST

0.09

0.54

0.86

  1. To account for Chi8’s sensitivity to univariate significant SNPs we only consider reported pairs where both SNPs are also individually insignificant
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BMC Research Notes

ISSN: 1756-0500

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