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Fig. 2 | BMC Research Notes

Fig. 2

From: Cause-effect relations between 55 kD soluble TNF receptor concentrations and specific and unspecific symptoms in a patient with mild SLE disease activity: an exploratory time series analysis study

Fig. 2

Cross-correlational functions (CCF) between urinary sTNF-R55 levels and SLE-related symptoms. a Urinary sTNF-R55 levels with urinary protein, b urinary sTNF-R55 levels with oral ulcers (binary-coded), c urinary sTNF-R55 levels with facial rash (binary-coded). Each lag represents a time interval of 12 h. Plots show cross-correlation coefficients (bars) as well as upper and lower limits of the 95 % confidence intervals. Significance level is p < 0.05. A positive lag significance means that urinary sTNF-R55 levels precede SLE-related symptoms (effect after sTNF-R55 change), whereas a negative lag significance means that SLE-related symptoms precede urinary sTNF-R55 levels (effect before sTNF-R55 change). In a and b there is a clear change in the sign of the cross-correlation function between positive and negative lags, indicating negative feedback loops

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BMC Research Notes

ISSN: 1756-0500

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