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Table 2 Average relative risk increase due to specific risk factor for each included risk calculator among non-diabetic patients (relative risk increase ± standard deviation)

From: Variation among cardiovascular risk calculators in relative risk increases with identical risk factor increases

Risk calculator Age (50–70) (%) Gender (female to male) (%) Smoking (non-smoker to smoker) (%) Systolic BP (120–160 mmHg) (%) Total chol (4–7 mmol/L) (%) HDL (1.3–0.8 mmol/L) (%)
Edinburgh (Framingham CVD) 112 ± 35 44 ± 12 70 ± 24 73 ± 25 51 ± 17 42 ± 14
Edinburgh (ASSIGN) 222 ± 53 35 ± 28 37 ± 8 49 ± 6 60 ± 21 27 ± 3
Primary CVD risk calculator 103 ± 31 56 ± 18 59 ± 15 69 ± 17 66 ± 20 56 ± 19
Framingham Heart Study 121 ± 23 91 ± 33 67 ± 11 83 ± 26 78 ± 13 41 ± 7
QRISK2-2011 335 ± 91 53 ± 20 57 ± 20 30 ± 17 51 ± 15 43 ± 14
Progetto CUORE 313 ± 30 141 ± 57 87 ± 27 75 ± 13 66 ± 26 29 ± 4
JBS Assessor 110 ± 35 48 ± 16 59 ± 15 43 ± 13 63 ± 19 54 ± 18
Edinburgh (BNF) 105 ± 31 56 ± 18 59 ± 13 71 ± 19 68 ± 22 56 ± 18
Reynolds Risk Score 344 ± 96 119 ± 82 83 ± 50 124 ± 44 89 ± 42 60 ± 35
Australian absolute CVD risk 153 ± 50 61 ± 20 95 ± 38 98 ± 37 65 ± 20 55 ± 19
New Zealand Know Your Numbers 154 ± 49 60 ± 19 95 ± 37 99 ± 37 60 ± 22 50 ± 21
UKPDS Risk Engine 182 ± 16 79 ± 8 31 ± 3 16 ± 2 77 ± 8 64 ± 6
i-phone STAT ATPIII lipid management 210 ± 228 225 ± 140 116 ± 110 72 ± 32 154 ± 124 61 ± 14
Edinburgh (Framingham CHD) 82 ± 32 64 ± 26 55 ± 16 51 ± 5 88 ± 26 73 ± 22
PROCAM Health Check 395 ± 204 114 ± 82 118 ± 27 35 ± 8 302 ± 67 133 ± 30
National Cholesterol Education Program 198 ± 203 201 ± 124 110 ± 125 69 ± 49 141 ± 129 61 ± 33
Overall average 196 ± 140 91 ± 80 75 ± 54 66 ± 37 92 ± 80 57 ± 30