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Table 5 Summary of average annual patient level direct costs evidence (CAN$)

From: Clinical, humanistic, and economic burden of chronic obstructive pulmonary disease (COPD) in Canada: a systematic review

References (study period)

Categories

Patient group

Patient perspective inflated cost/patient

Societal perspective inflated cost/patient

Chapman et al. [1] (12 months)

All

All

$2444.17

$3910.39

Gender

Male

$1941.09

$2817.88

Female

$2926.30

$4956.03

Smoking status

Former smokers

$3348.67

$4702.55

Current smokers

$1357.06

$2958.41

Comorbidities

Yes

$2506.92

$4568.22

No

$2370.68

$3127.96

Education status

Less educated

$3043.48

$4540.89

More educated

$2142.85

$3638.46

Wouters et al. [37] (1 year)

All

All

$2378.59

$6693.37

Gender

Male

NR

$2741.62

Female

NR

$4254.24

Smoking status

Former smokers

NR

$4575.67

Current smokers

NR

$2877.75

Education status

Less educated

NR

$4418.73

Well educated

NR

$3539.53

Mittmann et al. [3] (52 weeks)

Moderate exacerbation

ITT population

$718.48

NR

Clinically evaluable population

$847.38

NR

Severe exacerbation

ITT population

10,712.14

NR

Clinically evaluable population

11,156.01

NR

Maleki-Yazdi et al. [59] (Oct 2009 and Jan 2010)

All

All

$4391.16

NR

Acute exacerbation

Clinically evaluable population

$3214.75

NR

  1. ITT intention to treat, NR not reported