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Table 5 Mean comparison of symptoms measured by VHNSS 2.0 between patients groups (known-groups analysis)

From: The Vanderbilt Head and Neck Symptom Survey Brazilian Portuguese version 2.0 (VHNSS 2.0): psychometric properties for patients with head and neck cancer who have undergone radiotherapy

Domains

Radiotherapy

Staging

Surgery

Tumor site

> 6 and ≤12 months

>12 months

p value

I/II

III/IV

p value

No

Yes

p value

Oral cavity/oropharynx

Hypopharynx/larynx

p value

Média (DP) (n = 52)

Média (DP) (n = 185)

Média (DP) (n = 70)

Média (DP) (n = 163)

Média (DP) (n = 125)

Média (DP) (n = 116)

Média (DP) (n = 118)

Média (DP) (n = 123)

Nutrition

2.11 (2.26)

1.02 (1.72)

<0.001

0.96 (1.99)

1.34 (1.85)

0.005

1.18 (2.00)

1.30 (1.74)

0.295

1.88 (2.16)

0.63 (1.33)

<0.001

Swallowing solids

3.40 (2.19)

2.43 (2.19)

0.002

1.88 (2.41)

2.92 (2.9)

<0.001

2.32 (2.33)

2.96 (2.04)

0.002

3.32 (2.29)

1.95 (1.92)

<0.001

Swallowing liquids

0.95 (1.68)

0.84 (1.77)

0.354

1.04 (1.83)

0.78 (1.69)

0.052

0.80 (1.79)

0.93 (1.69)

0.318

1.07 (1.94)

0.65 (1.49)

0.103

Dry mouth

5.00 (2.52)

2.95 (2.60)

<0.001

2.31 (2.64)

3.78 (2.66)

<0.001

3.22 (2.78)

3.55 (2.65)

0.238

4.31 (2.81)

2.47 (2.29)

<0.001

Mouth pain

1.23 (1.84)

0.63 (1.40)

0.002

0.72 (1.61)

0.77 (1.46)

0.449

0.76 (1.70)

0.76 (1.30)

0.116

1.12 (1.76)

0.41 (1.13)

<0.001

Mucus

1.58 (1.77)

1.23 (1.91)

0.111

1.12 (1.95)

1.37 (1.83)

0.227

1.26 (2.07)

1.33 (1.62)

0.076

1.37 (1.96)

1.21 (1.76)

0.893

Voice

3.57 (2.61)

2.33 (2.55)

0.001

2.17 (2.33)

2.81 (2.71)

0.200

2.47 (2.85)

2.72 (2.30)

0.157

2.54 (2.65)

2.62 (2.55)

0.462

General pain

1.70 (2.39)

1.00 (2.01)

0.016

0.87 (2.02)

1.26 (2.16)

0.055

1.27 (2.29)

0.98 (1.87)

0.644

1.36 (2.24)

0.90 (1.93)

0.051

Hearing

2.08 (3.12)

1.69 (3.03)

0.125

1.66 (2.98)

1.71 (3.01)

0.893

1.97 (3.23)

1.57 (2.84)

0.33

1.76 (3.02)

1.78 (3.08)

0.983

Taste/smell

2.51 (2.18)

1.18 (1.82)

<0.001

0.95 (1.72)

1.68 (2.04)

0.001

1.40 (2.07)

1.53 (1.85)

0.129

1.88 (2.10)

1.05 (1.74)

<0.001

Trismus

2.02 (3.03)

1.41 (2.64)

0.181

1.34 (2.93)

1.61 (2.64)

0.167

1.23 (2.66)

1.86 (2.76)

0.018

2.62 (3.17)

0.48 (1.62)

<0.001

Neck

1.44 (2.58)

1.45 (2.62)

0.900

0.97 (2.14)

1.56 (2.65)

0.118

1.17 (2.36)

1.72 (2.80)

0.105

1.82 (2.95)

1.06 (2.13)

0.055

Teeth*

2.36 (2.50)

2.31 (2.12)

0.812

1.90 (1.95)

2.67 (2.44)

0.087

1.88 (1.95)

2.99 (2.51)

0.005

2.94 (2.50)

1.97 (2.02)

0.018

  1. Mann–Whitney Test. * Teeth domain: sample size varies depending on the subgroups (Staging I/II = 51, III/IV = 92; Oral cavity/oropharynx = 60, Hypopharynx/Larynx = 87, Radiotherapy >6 and ≤12 months = 31, >12 months = 114; Non-surgical = 82 and surgical = 65)
  2. Statistically significant p values at the 0.05 level are in italics