Fig. 1

Predicting functional interactions of unannotated proteins. To further investigate the function of the protein family whose members were all unannotated, Group 40 (Additional file 1), functional interactions were investigated using the STRING database. It was found that P. amoebophilia Q6MEA2 (a STRING ID pc0373) and C. trachomatis Q3KL42 (b STRING ID CTA_0708) both interact with the (putative) exodeoxyribonuclease V alpha chain with a high confidence score. Each query protein is in the centre of the interaction web and is coloured red. Grey dots in the key represent strength of evidence (darker is stronger). The sum of each distinct evidence type was used to generate the total score