Comparison of the protein-coding gene content of Chlamydia trachomatis and Protochlamydia amoebophila using a Raspberry Pi computer

Table 2 Differences in proteins produced, excluding shared single copy proteins

Protein relationship	Group number	Protein name
Unique to P. amoebophila *1	1	F-box
	2	Transposases
	3	Putative tetratricopeptide repeat protein
	4	Sel1 repeat protein4
	5	Transposases
Unique to C. trachomatis	10	Polymorphic outer membrane protein
	16	*2 Effector from type III secretion system
	70	Polymorphic outer membrane protein
	71	Hypothetical membrane associated protein
	72	Hypothetical membrane associated protein
	148	Deubiquitinase and deneddylase
	149	Biotin synthase
	150	*3 Threonine-rich GPI-anchored glycoprotein
	151	Outer membrane proteins
Single in C. trachomatis but multiple in P. amoebophila	11	Virulence plasmid integrases
	18	Low calcium response proteins
	19	Pb, Cd, Zn and Hg transporting ATPases
	36	Excinuclease ABC subunit A
	38	Chaperonins
	39	Putative antibiotic transporter
	40	*4
	41	Nucleoside diphosphate kinases
Single in P. amoebophila but multiple in C. trachomatis	9	Phosphatidylcholine-hydrolyzing phospholipase D (PLD) family
Multiple in both species	8	Tyrosine-specific transport protein

Protein families are uniquely identified by arbitrary group numbers, whose member proteins’ accession numbers are given in Additional file 1. For notes numbered *2 to *4, see Table 3. *1 In this category, only the largest five groups are shown. All proteins within these five groups were putative and uncharacterised, probable protein function was obtained by finding homologs on UniProtKB with >50 % sequence identity. For group three, although no homologs were found with >50 % sequence identity, it is possible that they are tetratricopeptide proteins as all within this group showed >30 % sequence identity to various tetratricopeptide proteins

ISSN: 1756-0500