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Table 6 DTI measures of white matter tracts in HIV positive patients with history of psychostimulant use

From: White matter deficits assessed by diffusion tensor imaging and cognitive dysfunction in psychostimulant users with comorbid human immunodeficiency virus infection

 

Controls (n = 22)

Patients (n = 20)

Effect size (d) and p value

Genu of CC

 FA

0.3838 ± 0.0254

0.3517 ± 0.0289

1.184; 0.0001*

 MD

0.910 ± 0.054

0.951 ± 0.039

−0.864; 0.008*

 AD

1.283 ± 0.071

1.301 ± 0.047

−0.296; 0.324

 RD

0.723 ± 0.052

0.775 ± 0.046

−1.056; 0.002*

Right ALIC

 FA

0.3555 ± 0.0229

0.3391 ± 0.0233

0.710; 0.027*

 MD

0.907 ± 0.064

0.953 ± 0.060

−0.740; 0.022*

 AD

1.245 ± 0.071

1.288 ± 0.061

−0.647; 0.044*

 RD

0.737 ± 0.064

0.785 ± 0.063

−0.756; 0.020*

Left ALIC

 FA

0.3798 ± 0.0307

0.3539 ± 0.0190

1.002; 0.002*

 MD

0.857 ± 0.055

0.914 ± 0.042

−1.157; 0.001*

 AD

1.208 ± 0.061

1.254 ± 0.049

−0.827; 0.011*

 RD

0.681 ± 0.058

0.745 ± 0.042

−1.254; 0.0001*

AC

 FA

0.3782 ± 0.0499

0.3509 ± 0.0332

0.638; 0.042*

 MD

1.107 ± 0.189

1.142 ± 0.200

−0.180; 0.558

 AD

1.539 ± 0.187

1.555 ± 0.239

−0.075; 0.773

 RD

0.937 ± 0.184

0.893 ± 0.191

0.235; 0.455

  1. Numbers indicate mean score (±SEM) for fractional anisotropy (FA), medial diffusivity (MD), axial diffusivity (AD) and radial diffusivity (RD) values for either the patient or control group; units for MD, AD and RD are (mm2/s × 10−3). Tracts include the genu of the corpus callosum (CC), left and right anterior limb of the internal capsule (ALIC) and the anterior commissure (AC). Values represent group mean ± SD
  2. * Significant difference between groups p < 0.05