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Table 2 Factors associated with depression (bivariate and multivariate) analysis, at UoGH, 2014

From: Depression among people with epilepsy in Northwest Ethiopia: a cross-sectional institution based study

Explanatory variables

Depression

Yes N (%) No N (%)

COR (95 % CI)

AOR (95 % CI)

P value

Age

 18–24

66 (40) 99 (60)

0.67 (0.305, 1.455)

  

 25–34

51 (41.5) 72 (58.5)

0.71 (0.318, 1.577)

  

 35–44

51 (58.6) 36 (41.4)

1.42 (0.616, 3.259)

  

 ≥45

15 (50) 15 (50)

1

  

Educational status

 Can’t read and write

57 (48.7) 60 (51.3)

5.70 (2.233, 14.551)

8.32 (4.826, 14.294)**

<0.001

 Primary

90 (46.2) 105 (53.8)

5.14 (2.072, 12.763)

6.02 (3.727, 9.292)**

<0.001

 Secondary

30 (58.8) 21 (41.2)

8.57 (3.064, 23.974)

4.00 (4.102, 8.251)**

0.005

 College and above

6 (14.3) 36 (85.7)

1

1

 

Social support

    

 High

105 (42.2) 144 (57.8)

1

  

 Moderate

42 (45.2) 51 (54.8)

1.13 (0.699, 1.825)

  

 Low

36 (57.142.9) 27 (6.7)

1.83 (1.046, 3.197)

  

Perceived stress

 Low

51 (27) 138 (73)

1

1

<0.001

 High

132 (61.1) 84 (38.9)

4.25 (2.789, 6.484)

6.21 (3.691, 10.442)**

 

Age at onset of the disease in year

 <6

15 (83.3) 3 (0.716.7)

2.50 (0.625, 9.996)

5.29 (4.086, 15.894)**

<0.001

 6–11

24 (53.3) 21 (46.7)

0.57 (0.244, 1.341)

0.95 (0.287, 3.169)

0.939

 12–17

36 (32.4) 75 (67.6)

0.24 (0.115, 0.501)

0.55 (0.213, 1.413)

0.214

 18–24

45 (40.5) 66 (59.5)

0.34 (0.165, 0.705)

0.85 (0.343, 2.153)

0.734

 25–34

33 (44) 42 (56)

0.39 (0.182, 0.848)

0.84 (0.330, 2.153)

0.720

 ≥35

30 (66.7) 15 (33.3)

1

1

 

Seizure frequency per year

 0

21 (25) 63 (75)

1

1

1

 1–11 per year

147 (50.5) 144 (49.5)

3.06 (1.776, 5.280)

1.34 (1.414, 4.360)**

0.022

 ≥12per year

15 (50) 15 (50)

3.00 (1.257, 7.157)

7.83 (3.523, 17.400)**

<0.001

Therapy (number of drug)

    

 Mono-pharmacy

132 (42.7) 177 (57.3)

1

1

<0.001

 Poly-pharmacy

51 (53.1) 45 (46.9)

5.34 (1.484, 19.389)

7.63 (2.741, 21.264)**

 

Difficulties of adherence to AEDs

 Yes

81 (61.4) 51 (38.6)

2.66 (1.736, 4.083)

4.80 (2.568, 8.964)**

<0.001

 No

102 (37.4) 171 (62.6)

1

1

 

Family history of mental illness

 Yes

9 (50) 9 (50)

1.22 (0.476, 3.151)

  

 No

174 (40.3) 258 (59.7)

1

  
  1. ** Statistically significant using a forward stepwise regression method with p value of Hosmer and Lemeshow goodness fit test 0.344