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Fig. 1 | BMC Research Notes

Fig. 1

From: Melanocortin agonists stimulate lipolysis in human adipose tissue explants but not in adipocytes

Fig. 1

Non-esterified fatty acid (NEFA) and glycerol release in intact adipose tissue explants from human. a NEFA release was measured after stimulation with increasing doses of isoproterenol or the indicated melanocortin peptide (100 nM–10 μM) in subcutaneous explants from non-obese females. The mean of 6 independent experiments (α-MSH, 3 independent experiments) in triplicate wells (mean ± SEM) are shown. b Glycerol release was measured after stimulation with increasing doses of isoproterenol or the indicated melanocortin peptide (100 nM–10 μM) in subcutaneous explants from non-obese females. The mean of 2 independent experiments in triplicate wells (mean ± SEM) are shown. Unpaired one-tailed t test was used to calculate statistical significance (*p < 0.05, **p < 0.01, ***p < 0.001 vs. vehicle)

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