Skip to main content

Table 3 Univariate logistic regression model of demographic and imaging determinants of cognitive dysfunction among subjects

From: Medial temporal lobe atrophy, white matter hyperintensities and cognitive impairment among Nigerian African stroke survivors

 

Normal vs vCIND

vCIND vs PSD

Normal vs (vCIND + PSD)

OR

95 % CI

p value*

OR

95 % CI

p value*

OR

95 % CI

p value*

Age >60 years

3.21

0.98–10.45

0.053

2.54

0.42–15.21

0.308

3.97

1.30–12.13

0.016

Female gender

2.24

0.72–6.95

0.163

1.19

0.23–6.17

0.835

2.34

0.81–6.74

0.116

Education <7 years

6.67

1.92–23.18

0.003

3.50

0.37–33.56

0.277

8.52

2.58–23.12

<0.001

Total WMH score

1.06

0.97–1.13

0.123

1.02

0.95–1.09

0.580

1.06

1.00–1.13

0.073

Periventricular WMH score

1.20

0.92–1.57

0.181

1.10

0.76–1.60

0.610

1.22

0.96–1.56

0.102

Deep WMH score

1.06

0.98–1.15

0.145

1.02

0.95–1.10

0.600

1.07

0.99–1.15

0.094

Log_ICV

0.22

0.001–5462.00

0.809

0.02

0.001–10,385.0

0.247

0.01

0.001–1144.1

0.439

Log_TBV

0.04

0.01–137.28

0.230

0.03

0.01–0.023

0.024

0.04

0.01–0.20

0.025

Log_VenVol

13.44

0.52–347.02

0.117

1.22

0.020–74.90

0.924

18.6

0.81–429.36

0.067

MTLA rating

1.91

1.19–3.06

0.007

1.10

0.59–2.07

0.759

2.05

1.28–3.27

0.003

  1. vCIND vascular cognitive impairment no dementia, PSD post-stroke dementia, CSID Community Screening Instrument for Dementia, MMSE Minimental State Examination, V-NB vascular neuropsychological battery, ICV intracranial volume, TBV total brain volume, VenVol ventricular volume, MTA medial temporal lobe atrophy rating, WMH white matter hyperintensity, OR odds ratio, CI confidence interval
  2. * p value = significant p values are in italics