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Table 3 Comparison between Ziehl Neelson (ZN) and Light Emitting Diode-Fluorescence Microscopic technique (LED-FM) in detecting AFB (by smear quantification) during follow-up of TB patients in eight medical colleges of India

From: Light Emitting Diode Fluorescence Microscopy increased the detection of smear-positives during follow-up of Tuberculosis patients in India: program implications

Smear grade of patient

ZN Microscopy 2011

LED-FM 2012

Change in percentage (95 % CI)

p-value

n1

%

n2

%

Negative

 

2604

95.0

2655

92.6

−2.4 (−1.1 to −3.7)

<0.0001

Positive

Scanty

33

1.2

75

2.6

1.4 (0.7–2.0)

0.0001

 

1+

57

2.1

78

2.7

0.6 (−0.1 to 1.4)

0.14

 

2+

29

1.1

27

0.9

−0. 2 (−0. 7 to 0. 4)

0.45

 

3+

17

0.6

33

1.1

0.5 (0.0 to 1.0)

0.01

Total

 

2740

100.0

2868

100.0

  1. ZN Ziehl Neelsen Microscopy, LED-FM light emitting diode fluorescence microscopy, AFB acid fast bacilli