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Table 1 Model parameter statistics from the logistic regression of the five test extracts against promastigotes of L. major

From: Evaluation of leishmanicidal activity and cytotoxicity of Ricinus communis and Azadirachta indica extracts from western Kenya: in vitro and in vivo assays

Test drug

Model

Parameter significance

A. indica

Log (ρ/1 − ρ) = 0.434 + 0.384 × C − 0.0008 × C2 + 0.0001 × C3

β0(0.0000) β1(0.0000) β2(0.0001) β3(0.0026)

R. communis

Log (ρ/1 − ρ) = 0.225 + 0.324 × C − 0.0008 × C2 + 0.0008 × C3

β0(0.0000) β1(0.0000) β2(0.0002) β3(0.0123)

Az + Rc

Log (ρ/1 − ρ) = 0.125 + 0.454 × C − 0.0008 × C2 + 0.0011 × C3

β0(0.0000) β1(0.0000) β2(0.0003) β3(0.0016)

AMB

Log (ρ/1 − ρ) = 0.015 + 0.684 × C − 0.0008 × C2 + 0.0004 × C3

β0(0.0000) β1(0.0000) β2(0.0004) β3(0.0021)

Pentostam

Log (ρ/1 − ρ) = 0.012 + 0.724 × C − 0.0008 × C2 + 0.0014 × C3

β0(0.0000) β1(0.0000) β2(0.0001) β3(0.0089)

  1. Az + Rc, combination of R. communis and A. indica; AMB, amphotericin B
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BMC Research Notes

ISSN: 1756-0500

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