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Table 4 Multiple drug resistant strains recovered from blood cultures of cancer patients

From: Bloodstream infections in patients with malignancies: implications for antibiotic treatment in a Ghanaian tertiary setting

Microorganism Multiple drug resistant isolates (%)
Total Period 1 Period 2
Number CTX-R CTX-S p value Number CTX-R CTX-S p value
Gram negatives (n = 49) a34/49 (69.3) a15/25a (60.0) 9/15 6/15 0.273 a19/24a (79.2) 16/19 3/19 <0.001
 Enterobacteriaceae (n = 32) 28/32 (87.5) 12/16a (75.0) 7/12 5/12 0.414 16/16b (100.0) 13/16 3/16 <0.001
  Escherichia coli (n = 8) 8/8 (100) 5/5a (100) 3/5 2/5 0.527 3/3a (100) 1/3 2/3 0.414
  K. pneumoniae (n = 3) 3/3 (100) 0 0 0 3/3 (100) 3/3 0/3 0.014
  Citrobacter species (n = 12) 9/12 (75.0) 5/8a (62.5) 3/5 2/5 0.527 4/4a (100) 4/4 0/4 0.004
  Enterobacter species (n = 7) 7/7 (100) 1/1a (100) 1/1 0/1 5/6a (100) 5/6 0/6 <0.001
  Providencia species (n = 1) 0/1 (0.0) 0/1 0 0 0 0 0
  Salmonella typhimurium (n = 1) 1/1 (100) 1/1 (100) 0/1 1/1 0 0 0
 Acinetobacter species (n = 7) 6/7 (85.7) 3/3a (100) 2/3 1/3 0.414 3/4a (75) 3/4 0/4 0.028
 Pseudomonas aeruginosa (n = 10) 0/10 (0.0) 0/6a (0.0)   0/4a (0.0)  
Gram positives (n = 40) b6/40 (15.0) b1/22a (4.5)   b5/18b  
  Enterococcus species (n = 2) 1/2 (50.0) 1/1a (50.0)   0/1a (0.0)  
  Staphylococcus aureus (n = 4) 1/4 (25.0) 0/3a (0.0)   1/1a (100)  
  Staphylococcus epidermidis (n = 28) 2/28 (7.2) 0/16a (0.0)   2/12a (16.7)  
  Streptococcus species (n = 6) 2/6 (33.3) 1/2a (50.0)   1/4a (25.0)  
Total 39/89 (43.9) 16/47a (34.1)     23/42b (54.7)    
  1. Numbers with differing superscripts within antimicrobial agent are significantly different at the p < 0.05
  2. CTX-R cefotaxime (30 μg) resistant, CTX-S cefotaxime susceptible, Period 1 first study period, Period 2 second study period