Skip to main content

Table 5 Differences in BSI caused by Gram positive and Gram negative bacteria, and between MDRs and non-MDRs

From: Bloodstream infections in patients with malignancies: implications for antibiotic treatment in a Ghanaian tertiary setting

Variables Number Antibiotic resistance
MDRs (n = 40) Non-MDRs (n = 49) Odds ratio (95 % CI) p value
Univariate analysis      
 Male gender      
  Yes 55 23 32 0.72 (0.31–1.69) 0.450
  No 34 17 17   
 Age (± SD)   24.05 ± 2.41 31.09 ± 3.32 0.21 (0.19–0.79) <0.001
 Paediatric patients      
  Yes 58 20 38 0.29 (0.11–0.72) 0.007
  No 31 20 11   
 Cancer type      
  Leukemia 32 14 18 0.93 (0.9–2.21) 0.862
  Lymphoma 15 7 8 1.08 (0.35–3.30) 0.887
  Myeloma 4 1 3 0.39 (0.04–3.93) 0.624
  Solid cancer 10 4 6 0.79 (0.21–3.04) 1
  Undiagnosed 26 12 14 1.07 (0.43–2.68) 0.887
 Haematologic cancers      
  Yes   31 23 3.89 (1.53–9.86) 0.003
  No   9 26   
 Febrile neutropenia 21 10 11 1.15 (0.43–3.07) 0.778
 Others 68 30 38   
 Year of infection      
  2010 18 8 10 0.97 (0.34–2.76) 1
  2011 29 16 15 1.51 (0.63–3.63) 0.353
  2012 31 17 14 1.84 (0.76–4.46) 0.17
  2013 11 5 6 1.02 (0.29–3.63) 1
 Patient location      
  Child health 46 20 26 0.86 (0.38–2.04) 0.778
  Haematology 25 12 13 1.18 (0.47–2.99) 0.718
  Others 15 7 8 1.08 (0.36–3.31) 0.887
 CTX resistance      0.001
  Yes 40 26 14 4.64 (1.89–11.39)  
  No 49 14 35   
 Gram negatives      
  Yes 49 34 15 12.8 (4.45–37.05) <0.001
  No 40 6 34   
 Enterobactericeae      
  Yes 32 28 4 26.2 (7.70–89.44) <0.001
  No 57 12 45   
 Pseudomonads      
  Yes 10 0 10 0.004
  No 79 40 39   
 Multivariate factor(s)      
  Enterobacteriaceae 33.6 (6.41–88.73) <0.001   
  1. Odds ratio in multivariate analysis were adjusted for age, paediatric patients, cefotaxime resistance, Gram-negative bacteria, Enterobacteriaceae and Pseudomonads
  2. MDRs multidrug resistant strains, CI confidence interval, SD standard deviation, CTX cefotaxime