Surgical versus medical management of patients with acute ischemic mitral regurgitation: a systematic review

BMC Research Notes

Table 1 Summary and pooled analysis of non-randomized studies of patients presenting with acute ischemic mitral regurgitation

Study	Study type	Year	N	Age (years)	NYHA III–IV (%)	EF %	<30 day mortality (N)		1–12 months mortality^a (N)		1–15 year mortality^a (N)
Study	Study type	Year	N	Age (years)	NYHA III–IV (%)	EF %	MVR	No MVR	MVR	No MVR	MVR	No MVR
Nishimura [16]	Case series	1986	7	57	100	49	0/7	(–)	3/7	(–)	1/7	(–)
Kishon [17]^b	Retrospective	1992	22	68			6/22	(–)	(–)	(–)	6/22	(–)
Tcheng [9]	Retrospective	1992	50	68		35	(–)	16/50	(–)	25/50	(–)	(–)
Gillinov [18]	Retrospective	2001	95				7/95	(–)	6/95	(–)	74/95	(–)
Minami [19]^b	Retrospective	2004	6		100	57	2/6	(–)	(–)	(–)	(–)	(–)
Russo [20]^b	Prospective	2008	54	70	98	56	2/54	(–)	(–)	(–)	(–)	(–)
Lorusso [21]^b	Retrospective	2008	126	62	66	#	34/126	(–)	(–)	(–)	8/126	(–)
Thompson [6]	Prospective	2009	94	71	100	37	17/43	36/51	(–)	(–)	(–)	(–)
Pooled			454	67	91	42	68/353	52/101	9/102	25/50	89/252	(–)

EF ejection fraction, MVR mitral valve repair or replacement, N number of patients with acute ischemic mitral regurgitation, NYHA New York Heart Association
^#Half of patients had left ventricular systolic dysfunction; (–), not applicable or no patients enrolled in that arm
^aThese is not cumulative mortality. To get cumulative mortality, add up the numbers where applicable
^bMixed studies including patients with papillary muscle rupture

ISSN: 1756-0500