Fig. 1

Heatmap of our data matrix. The horizontal axis denotes InterPro signatures, whereas the vertical axis represents the enzyme sequence’s UniProt accession number and the corresponding MACiE enzymatic mechanism labels of the form M0123. The yellow colour signifies that feature x _i (InterPro signature) is present for the enzyme, while the red colour indicates that x _i is absent for this enzyme. Enzymes that possess the same MACiE mechanism label reside in a subspace of the feature space χ, which barely overlaps with other subspaces associated with other mechanisms. The inset depicts the heatmap for the dataset matrix corresponding to the InterPro signatures and names of enzymes with the MACiE enzymatic mechanism label M0218