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Table 4 Comparison of demographics between AIH patients with or without rs6000782 C allele

From: Lack of association between the CARD10 rs6000782 polymorphism and type 1 autoimmune hepatitis in a Japanese population

  rs6000782 C allele (+) rs6000782 C allele (−) p
n = 42 n = 284
Female, n (%) 38 (90.5) 251 (88.4) 0.465
Age, years, mean ± SD 59.6 ± 13.9 59.5 ± 13.3 0.786
Biochemistry
 AST, IU/L [median (IQR)] 189.0 (85.5–835.0) 264.0 (94.0–707.5) 0.620
 ALT, IU/L [median (IQR)] 258.5 (93.0–906.0) 305.0 (104.5–813.0) 0.926
 ALP, IU/L [median (IQR)] 402.5 (261.0–566.0) 437.0 (323.5–586.5) 0.242
 Total bilirubin, mg/dl [median (IQR)] 1.9 (0.8–4.6) 1.2 (0.8–4.6) 0.680
 Albumin, g/dl [median (IQR)] 3.9 (3.4–4.2) 3.9 (3.5–4.2) 0.844
 IgG, mg/dl [median (IQR)] 2078.0 (1695.0–2691.5) 2250.0 (1835.5–2945.0) 0.199
 Platelets, 104/μl [median (IQR)] 19.6 (15.1–22.4) 18.4 (13.9–23.1) 0.712
Serology
ANA 1:40, n (%) 36 (85.7) 252 (89.0) 0.339
ASMA 1:40, n (%) 13 (31.0) 108 (39.3) 0.301
Histology
 Cirrhosis, n (%) 8 (19.0) 43 (15.1) 0.515
  1. AST aspartate aminotransferase, ALT alanine aminotransferase, ALP alkaline phosphate, IgG immunoglobulin G, ANA anti-nuclear antibody, ASMA anti-smooth muscle antibody, IQR interquartile range