Table 4 Comparison of demographics between AIH patients with or without rs6000782 C allele
rs6000782 C allele (+) | rs6000782 C allele (−) | p | |
|---|---|---|---|
n = 42 | n = 284 | ||
Female, n (%) | 38 (90.5) | 251 (88.4) | 0.465 |
Age, years, mean ± SD | 59.6 ± 13.9 | 59.5 ± 13.3 | 0.786 |
Biochemistry | |||
AST, IU/L [median (IQR)] | 189.0 (85.5–835.0) | 264.0 (94.0–707.5) | 0.620 |
ALT, IU/L [median (IQR)] | 258.5 (93.0–906.0) | 305.0 (104.5–813.0) | 0.926 |
ALP, IU/L [median (IQR)] | 402.5 (261.0–566.0) | 437.0 (323.5–586.5) | 0.242 |
Total bilirubin, mg/dl [median (IQR)] | 1.9 (0.8–4.6) | 1.2 (0.8–4.6) | 0.680 |
Albumin, g/dl [median (IQR)] | 3.9 (3.4–4.2) | 3.9 (3.5–4.2) | 0.844 |
IgG, mg/dl [median (IQR)] | 2078.0 (1695.0–2691.5) | 2250.0 (1835.5–2945.0) | 0.199 |
Platelets, 104/μl [median (IQR)] | 19.6 (15.1–22.4) | 18.4 (13.9–23.1) | 0.712 |
Serology | |||
ANA ≧ 1:40, n (%) | 36 (85.7) | 252 (89.0) | 0.339 |
ASMA ≧ 1:40, n (%) | 13 (31.0) | 108 (39.3) | 0.301 |
Histology | |||
Cirrhosis, n (%) | 8 (19.0) | 43 (15.1) | 0.515 |