Retrospective analysis of the efficacy of chemotherapy and molecular targeted therapy for advanced pulmonary pleomorphic carcinoma

Table 2 Association between pathological findings and molecular profile

No.	Sex	Diagnostic procedure	Smoking index	EGFR mutation	KRAS mutation	ALK IHC	Pathological features
No.	Sex	Diagnostic procedure	Smoking index	EGFR mutation	KRAS mutation	ALK IHC	Epithelial component	Sarcomatoid component
1	M	Surgery	2100	Wild	Mutated	Negative	Adeno	Giant cell > Spindle cell
2	F	Surgery	0	Exon 19 del	Wild	Negative	Adenosquamous	Spindle cell > Giant cell
3	M	Surgery	1200	Wild	Wild	Negative	Adeno	Spindle cell > Giant cell
4	F	Surgery	0	Wild	Wild	Negative	Adeno	Spindle cell > Giant cell
5	M	Surgery	400	Wild	Wild	Negative	Adeno	Spindle cell > Giant cell
6	M	Surgery	1800	Wild	Wild	Negative	Squamous	Spindle cell > Giant cell
7	F	Surgery	600	Wild	Wild	Negative	Adeno	Spindle cell > Giant cell
8	F	Surgery	345	Wild	Mutated	Negative	Large	Giant cell > Spindle cell
9	M	Autopsy	495	NA	NA	NA	NOS	Giant cell > Spindle cell
10	M	Biopsy	2480	Wild	Wild	Negative	NOS	Giant cell
11	M	Autopsy	480	Wild	Wild	Negative	Adeno	Giant cell
12	M	Biopsy	1600	Wild	Mutated	Negative	Squamous	Spindle cell > Giant cell
13	M	Surgery	660	Wild	Wild	Negative	Large	Giant cell > Spindle cell
14	M	Autopsy	1160	Wild	Wild	Negative	Adeno	Giant cell > Spindle cell
15	F	Surgery	0	Exon 21 L858R	Wild	Negative	Large	Spindle cell > Giant cell
16	F	Biopsy	0	NA	NA	NA	Large	Spindle cell > Giant cell

IHC immunohistochemistry, NOS not otherwise specified, Adeno adenocarcinoma, Squamous squamous cell carcinoma, Large large cell carcinoma, Adenosquamous adenosquamous carcinoma

ISSN: 1756-0500