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Table 2 Distribution of MTHFR genotype according to patient’s family history

From: Association of methylenetetrahydrofolate reductase gene (C677T) with the risk of hypertension in Morocco

Family history C677T N (%) χ2 p
CC CT TT
Hypertension
 Yes 29 (50) 23 (39.7) 6 (10.3) 1.6 0.5
 No 18 (41.9) 17 (39.7) 8 (18.6)   
Heart disease
 Yes 8 (34.8) 8 (34.8) 7 (30.4) 6.9 0.031
 No 39 (50) 32 (41) 7 (9)   
Stroke
 Yes 7 (43.8) 7 (43.8) 2 (12.5) 0.14 0.9
 No 40 (47.1) 33 (38.8) 12 (14.1)   
Diabetes
 Yes 18 (40) 20 (44.4) 7 (15.6) 1.4 0.5
 No 29 (51.8) 20 (35.7) 7 (12.5)   
Kidney disease
 Yes 1 (12.5) 6 (75) 1 (12.5) 4.9 0.08
 No 46 (49.5) 34 (36.6) 13 (14)   
Dyslipidemia
 Yes 12 (48) 8 (32) 5 (20) 1.4 0.5
 No 35 (46.1) 32 (42.1) 9 (11.8)   
  1. CC homozygous wild type, CT heterozygous, TT homozygous variant