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Table 3 Distribution of genotypes and alleles of MTHFR in patients and controls

From: Association of methylenetetrahydrofolate reductase gene (C677T) with the risk of hypertension in Morocco

 

Patients N (%)

Control N (%)

OR (95 % CI)

p

C677T

 CC

47 (46.5)

54 (52.9)

Ref.

 

 CT

40 (39.6)

45 (44.2)

1 (0.6–1.8)

1

 TT

14 (13.9)

3 (2.9)

5.4 (1.4–19.8)

0.008

 CC/CTa

87 (86)

99 (97)

Ref.

 

 TT

14 (14)

3 (3)

5.3 (1.5–19.1)

0.005

 CCb

47 (46)

54 (53)

Ref.

 

 CT/TT

54 (54)

48 (47)

1.3 (0.7–2.2)

0.4

 C

134 (66)

153 (75)

Ref.

 

 T

68 (34)

51 (25)

1.5 (1–2.3)

0.06

 HWE: p value

0.27

0.11

  
  1. HWE Hardy–Weinberg Equilibrium, N number
  2. aRecessive model
  3. bDominant model