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Table 1 Summary of the investigations during the first 18 days of hospital stay

From: Clozapine induced pancytopenia leading to severe sepsis: an unusual early complication

Investigation D1 D2 D3 D4 D5 D6 D7 D8 D9 D10 D11 D12 D13 D14 D15 D16 D17 D18
WBC (×103/μl) 0.20 0.32 0.40 0.60 0.60 0.80 0.32 0.61 0.82 1.0 3.5 9.5 20 27.7 35.5 37.2 36.1 29.4
ANC (×103/μl) 0.11 0.10 0.16 0.09 0.12 0.14 0.14 0.28 0.15 0.34 1.8 6.9 16.5 21.6 28 29.6 31 25
Hb (g/dl) 12.2 11.1 10.7 11.5 9.6 9.5 8.9 8.4 8.7 8.1 8.8 8.7 8.3 8.4 8.5 8.2 7.1 8.4
RBC (×106/μl) 4.19 4.21 3.95 3.95 4.01 4.65 3.56 3.88 4.28 4.94 4.22 3.98 4.11 4.55 4.82 4.77 4.36 4.29
MCV (fL) 84 85 85.4 85.3 85.4 84 83.1 86 84.1 83.1 85 84.2 83.2 85 84.1 86 86.2 85.3
MCH (pg) 32.0 30.1 29.8 30 28.8 29.1 31 32.2 31.3 33 34 32.1 33.4 32 34 33.1 33 33.2
MCHC (g/dl) 34.9 35.1 34.9 35.2 33.7 34.4 35 35.2 33 34 33.2 34 33.2 35 35.2 34.8 33.8 32.7
PCV (%) 35 33 30 36 28 27 27 25 25 26 24 26 26 25 26 25 22 26
Plt (×103/μl) 97 79 53 82 75 64 70 57 89 144 196 247 254 232 212 200 201 283
ALT (IU/l)   43 42    35 63 58 60 53 48 56 62 49 38 23   30
AST (IU/l)   103 114    67 108 70 65 68 74 80 68 52 50 65   42
Alb (g/l)       22    23    28     26   
Prot (g/l)       44    56    60     60   
S cr (μmol/l)   56.2     71 75 64 51 47    66    73   68
BU (mmol/l) 15.7 14.9    9.3 7.0 6.7 4.3 4.3 4.6 3.8 4.2 5.0 4.8 3.8 2.5   
Na+ (mmol/l) 134 132    140 147 148 154 132 153 143 140 138 132 136 145 138 136
K+ (mmol/l) 4.4 3.6    3.5 3.8 3.3 3.4 4.1 5.3 4.8 3.9 4.0 3.1 3.0 3.2 4.1 4.8
CRP (mg/l)     270       30         34
  1. WBC white blood cells, ANC absolute neutrophil count, Hb hemoglobin, RBC red blood cell count, MCV mean corpuscular volume, MCH mean corpuscular hemoglobin, MCHC mean corpuscular hemoglobin concentration, PCV pack cell volume, Plt platelet, ALT alanine transaminase, AST aspartate transaminase, Alb albumin, Prot total protein, S cr serum creatinine, BU blood urea, Na + serum sodium, K + serum potassium, CRP C reactive protein