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Table 2 Endoscopic, surgical findings and outcome of patients with amebic colitis

From: Clinical manifestations and endoscopic findings of amebic colitis in a United States-Mexico border city: a case series

No. Procedure Location/distance Findings Histopathology Treatment Outcome
1 Surgery Terminal ileum, cecum, ascending colon Large cecal mass Extensive flask shaped ulcers with large abscesses with numerous hemophagocytic amebic trophozoites metronidazole 14 days 5 days later: colonic perforation secondary to amebiasis. Ileostomy. 1 year later: amebic liver abscess
2 Colonoscopy To transverse Multiple ulcers Amebiasis with deep ulcerations metronidazole 14 days + paromomycin 7 days Complete resolution of symptoms
3 Colonoscopy To splenic flexure Rectosigmoid ulceration/colitis Acute and chronic colitis. No amebic trophozoits found metronidazole 14 days + paromomycin 10 days 7 days later: amebic liver abscess
4 Colonoscopy To descending Severe rectosigmoid colitis/ulcerations Surface ulcerations covered by necrotic fibrinous exudate. Many amebic trophozoites in exudate metronidazole 14 days + paromomycin 20 days Complete resolution of symptoms
5 Colonoscopy To ileum Pancolitis/multiple ulcers Mucosal edema and ulcerations/necrosis with fibrinous exudate. Hemophagocytic amebic trophozoites in exudate metronidazole 14 days Discharged in good condition.
6 Colonoscopy To cecum Diffuse inflammation/pseudopolyps Acute and chronic colitis with superficial erosion/necrosis. Amebic trophozoites present metronidazole 14 days + paromomycin 10 days Amebiasis resolved. Diarrhea persists due to ulcerative colitis
7 Colonoscopy To ileum Pancolitis/multiple ulcers Acute colitis. Amebic trophozoites present metronidazole 14 days + iodoquinol 20 days Discharged in good condition.
8 Colonoscopy To cecum Pancolitis Acute and focal colitis. Amebic trophozoites present metronidazole 14 days Resolution of symptoms
9 Colonoscopy To hepatic flexure Fungating, ulcerated, partially obstructing mass in distal sigmoid colon Invasive Sigmoid Adenocarcinoma. Amebic trophozoites present metronidazole 14 days + paromomycin 7 days Chemotherapy
  1. RLQ right lower quadrant, LLQ left lower quadrant, ND not done, NS not stated