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Fig. 2 | BMC Research Notes

Fig. 2

From: Buserelin treatment to rats causes enteric neurodegeneration with moderate effects on CRF-immunoreactive neurons and Enterobacteriaceae in colon, and in acetylcholine-mediated permeability in ileum

Fig. 2

Numbers of neurons in submucosal (SG) and myenteric ganglia (MG) per mm length in fundus, ileum, and colon from rats treated with four sessions of saline (controls, C) or buserelin (B). Rats were euthanized 2 weeks after the fourth treatment session. Neuronal counting was performed on longitudinally cut, whole-wall sections. Rats subjected to four sessions of buserelin treatment showed decreased numbers of submucosal neurons in ileum (p < 0.05) and colon (p < 0.05), and myenteric neurons in fundus (p < 0.05), ileum (p < 0.01), and colon (p < 0.01), compared with controls. C = 7 rats and B = 11 rats. Results are presented as medians and interquartile ranges and were analyzed by the Mann–Whitney U-test. Statistical significance is indicated by *p < 0.05 and **p < 0.01

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BMC Research Notes

ISSN: 1756-0500

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