Toxicological study of the butanol fractionated root extract of Asparagus africanus Lam., on some blood parameter and histopathology of liver and kidney in mice

Table 2 Comparison of hematological parameters among fractionated extract of A. africanus treated groups at doses of 300 and 600 mg/kg body weight/day, and the control mice

Hematological parameter	Control	300 mg/kg bwt			600 mg/kg bwt
Hematological parameter	Control	Values	% of mean difference	P value	Values	% of mean difference	P value
RBC (×10⁶/µL)	10.93 ± 0.38	11.48 ± 0.46	4.79	0.596	11.33 ± 0.64	3.55	0.468
Hemoglobin (g/dL)	15.63 ± 0.75	16.47 ± 0.58	5.10	0.383	16.57 ± 0.75	5.67	0.433
Hematocrit (%)	56.97 ± 1.72	60.20 ± 2.29	5.37	0.756	56.05 ± 1.91	−1.61	0.294
MCV (fL)	52.17 ± 0.63	52.47 ± 1.27	0.57	0.662	52.83 ± 1.07	1.25	0.843
MCH (pg)	14.30 ± 0.21	14.33 ± 0.29	0.21	0.309	14.70 ± 0.27	2.72	0.929
MCHC (g/dL)	27.40 ± 0.59	27.37 ± 0.15	−0.11	0.593	27.80 ± 0.63	1.44	0.964
PLAT (10³/µL)	581.00 ± 38.2	702.67 ± 99.3	35.56	0.564	455.33 ± 288.7	−21.67	0.169
WBC (10³/µL)	4.76 ± 1.42	6.76 ± 2.36	29.59	0.352	7.97 ± 2.76	40.28	0.553

ISSN: 1756-0500