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Table 1 Pathological and bacteriological findings

From: Modelling severe Staphylococcus aureus sepsis in conscious pigs: are implications for animal welfare justified?

 

Gross pathology

Histology of liver

Bacteriology

Pigs

Inoculum infusion time

Euthanised (h)

Pneumoniaa

Nephritisb

Arthritisc

Auricular phlebitisd

Micro-abscesses

Hyaline globules

Bloode

Liver

Lung

Spleen

Bone marrow

Case-1

10 min

48

+

+

+

+

+

+

Case-2

3 min 20 s

30

+

+

+

+

+

+

Case-3

6 min 40 s

48

+

+

+

+

+

+

+

+

Case-4

6 min 40 s

48

+

+

+

+

+

+

+

+

Control-1

10 min

48

+

Control-2

3 min 20 s

48

+

+

+

  1. aAcute multifocal suppurative embolic pneumonia. Estimated number of lesions ranged between 10–60
  2. bAcute multifocal suppurative embolic nephritis. Number of lesions ranged from 1to 4 (bilaterally)
  3. cAcute fibrinous or fibrinosuppurative arthritis. Number of affected joints observed was one or two
  4. d S. aureus purulent phlebitis in left ear
  5. e S. aureus positive cultures were obtained at following sample time points: 6, 12, 24 h for Case-1; 12 h for Case-2; 48 h for Case-3; 24, 36 h for Case-4; 12 h for Control-2