Fig. 1
Effect of IL-17A on MMP-3 production by HS-SY-II cells. a Representative the mRNA level of MMP-3 in HS-SY-II cells stimulated with IL-17A. Data are expressed as the mean ± SD of triplicate cultures. *Indicates statistical significance of p < 0.01. b Western blot for MMP-3 in HS-SY-II cells stimulated with IL-17A. c Represents immunofluorescent staining for IL-17R in HS-SY-II cells. Merge image is digital three-color overlay of IL-17R (green), rhodamine isothiocynate-phalloidin (red), and DAPI detection of nuclei (blue). The bars indicate 100 μm. d Representative the mRNA level of MMP-3 in HS-SY-II cells pretreated with IL-17R Ab, followed by incubation with IL-17A. Data are expressed as the mean ± SD of triplicate cultures. *Indicates statistical significance of p < 0.01