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Table 1 Distribution of the polymorphisms in IL-1A, IL4, NFKB1 and PAR1 genes in Brazilian regions and parental populations

From: Distribution of allelic and genotypic frequencies of IL1A, IL4, NFKB1 and PAR1 variants in Native American, African, European and Brazilian populations

Genotypes North
No. (%)
Northeast
No. (%)
Midwest
No. (%)
Southeast
No. (%)
South
No. (%)
Native Americans
No. (%)
Africans
No. (%)
Europeans
No. (%)
IL1A
(rs3783553)
180 187 186 184 191 222 211 268
Ins/Ins 52 (28.9) 89 (47.6) 57 (30.6) 91 (49.5) 102 (53.4) 08 (13.5) 129 (61.1) 132 (33.7)
Ins/Del 92 (51.1) 77 (41.2) 100 (53.8) 74 (40.2) 70 (36.6) 65 (45.5) 71 (33.7) 111 (55.9)
Del/Del 36 (20.0) 21 (11.2) 29 (15.6) 19 (10.3) 19 (10.0) 149 (41.0) 11 (5.2) 25 (10.4)
Ins 0.545 0.682 0.575 0.696 0.717 0.182 0.780 0.700
Del 0.455 0.318 0.425 0.304 0.283 0.818 0.220 0.300
IL4
(rs79071878)
180 187 186 184 191 222 211 268
A3/A3 61 (33.9) 109 (58.3) 104 (55.9) 98 (53.3) 114 (60.0) 12 (5.4) 22 (10.4) 143 (53.3)
A3/A2 89 (49.4) 72 (38.5) 70 (37.6) 78 (42.4) 69 (36.3) 77 (34.7) 133 (63.0) 109 (40.7)
A2/A2 30 (16.7) 06 (3.2) 12 (6.5) 08 (4.3) 07 (3.7) 133 (59.9) 56 (26.6) 16 (6.0)
A3 0.586 0.775 0.747 0.745 0.782 0.227 0.420 0.737
A2 0.414 0.225 0.253 0.255 0.218 0.773 0.580 0.263
NFKB1
(rs28362491)
180 187 185 184 191 222 211 268
Ins/Ins 34 (18.9) 75 (40.0) 62 (33.5) 61 (33.2) 73 (38.2) 30 (13.5) 47 (22.3) 90 (33.6)
Ins/Del 99 (55.0) 80 (43.0) 88 (47.6) 88 (47.8) 93 (48.7) 101 (45.5) 109 (51.7) 151 (56.3)
Del/Del 47 (26.1) 32 (17.0) 35 (18.9) 35 (19.0) 25 (13.1) 91 (41.0) 55 (26.0) 27 (10.1)
Ins 0.464 0.615 0.573 0.571 0.626 0.363 0.481 0.617
Del 0.536 0.385 0.427 0.429 0.374 0.637 0.519 0.383
PAR1
(rs11267092)
180 187 186 183 191 222 199 267
Ins/Ins 11 (6.1) 17 (9.1) 18 (9.8) 22 (12.0) 16 (8.4) 02 (0.9) 56 (28.1) 12 (4.5)
Ins/Del 56 (31.1) 76 (40.6) 67 (36.0) 64 (35.0) 61 (31.9) 17 (7.7) 86 (43.2) 98 (36.7)
Del/Del 113 (62.8) 94 (50.3) 101 (54.3) 97 (53.0) 114 (59.7) 203 (91.4) 57 (28.7) 157 (58.8)
Ins 0.217 0.294 0.277 0.295 0.243 0.047 0.497 0.228
Del 0.783 0.706 0.723 0.705 0.757 0.953 0.503 0.772