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Fig. 2 | BMC Research Notes

Fig. 2

From: Effector function of CTLs is increased by irradiated colorectal tumor cells that modulate OX-40L and 4-1BBL and is reversed following dual blockade

Fig. 2

Tumor cells modulate OX-40L protein expression after treatment with radiation. a Irradiated (5 and 10 Gy) and non-irradiated (0 Gy) WiDr colorectal carcinoma cells were stained with PE-labeled antibody to human OX-40L. Isotype control staining is shown in gray filled histogram. OX-40L-PE positive cells are shown in solid black line histogram. b OX-40L expression in five additional tumor cell lines receiving 10 Gy (black bar) or 0 Gy (gray bar). *P value <0.05. Data graphed are the mean of two (Caco2), three (HCT116, Colo205, HT-29) or four (SW620) experimental repeats and error bars represent the SEM across the independent experiments

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