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Table 1 Demographic data and presenting symptoms of HSV encephalitis in patients with CSF pleocytosis and patients with normocellular CSF

From: Normocellular CSF in herpes simplex encephalitis

Demographic data CSF pleocytosis group (WBC > 5cells/mm3) Normocellular CSF group (WBC ≤ 5cells/mm3)
Number of patients 17 6
Male:female 9:8 1:5
Median age (years) [range] 35 [1–59] 41 [27–85]
Underlying disease
 Normal 13 (76.5 %) 3 (50 %)
 HIV infection 0 1 (16.7 %)
 Diabetes mellitus 2 (11.8 %) 0
 Hematologic malignancy 2 (11.8 %) 0
 Multiple Sclerosis (MS) 0 1 (16.7 %)
 Systemic Lupus Erythematosus (SLE) 0 1 (16.7 %)
Prodrome
 Fever 1 (5.9 %) 1 (16.7 %)
 Fever with headache 9 (52.9 %) 1 (16.7 %)
 Fever with myalgia 1 (5.9 %) 1 (16.7 %)
 Upper respiratory tract symptoms 1 (5.9 %) 0
 Fever with diarrhea 1 (5.9 %) 0
 Fever with non-specific rash 1 (5.9 %) 0
 Headache 2 (11.8 %) 0
 Non-specific 1 (5.9 %) 3 (50 %)
Presenting symptoms
 Worsening headache with/without neck stiffness 2 (11.8 %) 0
 Hemiparesis 1 (5.9 %) 0
 Facial weakness 1 (5.9 %) 0
 Severe spastic body and limbs 1 (5.9 %) 0
 Behavioral change and confusion 4 (23.5 %) 3 (50 %)
 Seizures 5 (29.4 %) 2 (33.3 %)
 Alteration of consciousness 3 (17.6 %) 1 (16.7 %)
Outcome
 Complete recovery 5 (29.4 %) 1 (16.7 %)
 Partial recovery 10 (58.8 %) 4 (66.7 %)
 Dead 2 (11.8 %) 1 (16.7 %)