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Table 6 Effects of ethanol extract of S. jambos and indomethacin on carrageenan-induced oedema paw volume in wistar rats

From: HPLC profiling, antioxidant and in vivo anti-inflammatory activity of the ethanol extract of Syzygium jambos available in Bangladesh

Treatment Dose Right hind paw volume (% inhibition)
(mg/kg) 1 h 2 h 3 h 4 h 5 h
Vehicle 10 (ml/kg) 0.98 ± 0.12 1.07 ± 0.16 1.26 ± 0.21 1.35 ± 0.23 1.43 ± 0.25
Indomethacin 10 0.46 ± 0.15 (53.06)* 0.47 ± 0.19 (56.07)* 0.53 ± 0.17 (57.94)* 0.54 ± 0.16 (60.00)* 0.53 ± 0.18 (62.94)**
S. jambos 200 0.74 ± 0.13 (24.49)* 0.69 ± 0.14 (35.51)* 0.74 ± 0.18 (41.27)** 0.75 ± 0.15 (44.44)* 0.73 ± 0.17 (48.95)**
S. jambos 400 0.65 ± 0.15 (33.67)* 0.58 ± 0.17 (45.79)** 0.59 ± 0.19 (53.18)** 0.61 ± 0.18 (54.82)* 0.60 ± 0.17 (58.04)**
  1. Each value is presented as the mean ± SEM (n = 5)
  2. P < 0.05 compared with control group (Dunnett’s test)
  3. ** P < 0.01 compared with control group (Dunnett’s test)