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Table 7 Effect of ethanol extract of S. jambos and indomethacin on histamine-induced oedema paw volume in wistar rats

From: HPLC profiling, antioxidant and in vivo anti-inflammatory activity of the ethanol extract of Syzygium jambos available in Bangladesh

Treatment Dose Right hind paw volume (% Inhibition)
(mg/kg) 1 h 2 h 3 h 4 h 5 h
Vehicle 10 (ml/kg) 1.10 ± 0.15 1.25 ± 0.19 1.34 ± 0.18 1.40 ± 0.22 1.52 ± 0.21
Indomethacin 10 0.56 ± 0.14 (49.09)* 0.57 ± 0.16 (54.40)* 0.58 ± 0.15 (56.72)* 0.53 ± 0.19 (62.14)** 0.52 ± 0.13 (65.79)**
S. jambos 200 0.76 ± 0.11 (30.91) 0.80 ± 0.17 (36.00)** 0.86 ± 0.23 (35.82)* 0.84 ± 0.15 (40.00)** 0.82 ± 0.18 (46.05)**
S. jambos 400 0.67 ± 0.13 (39.09) 0.69 ± 0.14 (44.80)* 0.72 ± 0.16 (46.27)* 0.74 ± 0.14 (47.14)* 0.70 ± 0.19 (53.95)**
  1. Each value is presented as the mean ± SEM (n = 5)
  2. P < 0.05 compared with control group (Dunnett’s test)
  3. ** P < 0.01 compared with control group (Dunnett’s test)