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Table 4 SuperPaths overrepresented among genes upregulated in the trophectoderm by CSF2

From: Regulation of gene expression in the bovine blastocyst by colony stimulating factor 2

Inhibitory actions of lipoxins on superoxide production in neutrophils (score = 25.39)—9 genes
 FOS, GNG12, GNG2, GNGT2, JUN, PLD1, NFKBIA, PIK3CG, PREX1
Translation regulation by alpha-1 adrenergic receptors (score = 19.66)—8 genes
 ADRA1A, FOS, GNG12, GNG2, GNGT2, JUN, PLD1, PRKCE
Hypertrophy model (score = 18.66)—5 genes
 ANKRD1, ATF3, CYR61, HBEGF, IFNG
Apoptotic pathways in synovial fibroblasts (score = 16.29)—22 genes
 ANK1, ARHGDIB, CACNA2D1, CTGF, FOS, GNG12, GNG2, GNGT2, HBEGF, ITGB3, JUN, KITLG, KLF10, MAP3K8, NFKBIA, NRP1, PLD1, PPARA, PPP1R14A, PRKCE, RHOB, ZAP70
G-protein signaling ras family gtpases in kinase cascades (score = 15.90) 8 genes
 CYR61, FOS, FOSB, JUN, LDLR, NFKBIA, PRKCE, SIPA1
Toll comparative pathway (score = 15.54) 8 genes
 ATF3, FOS, FOSB, GNG2, IFNG, IL1RAP, JUN, NFKBIA
ERK signaling (score = 15.12) 29 genes
 ARHGDIB, ATF3, CACNA2D1, CAPN11, CTGF, DUSP1, FOS, FOSB, GNG12, GNG2, GNGT2, HBEGF, IL17A, ITGB3, JUN, KITLG, KLF10, MAP3K8, NFKBIA, NRP1, PIK3CG, PLD1, PPP1R14A, PRKCE, RHOB, SMAD9, SPP1, TNFRSF8, ZAP70
Osteopontin-mediated events (score = 15.0)—5 genes
 FOS, ITGB3, JUN, NFKBIA, SPP1
ATF-2 transcription factor network (score = 14.65)—6 genes
 ATF3, DUSP1, DUSP5, FOS, IFNG, JUN
Angiotensin activation of ERK (score = 14.51)—11 genes
 FOS, GNG12, GNG2, GNGT2, HBEGF, KITLG, ITGB3, JUN, PIK3CG, PRKCE, ZAP70
LPA receptor mediated events (score = 13.79)—6 genes
 FOS, GNG2, HBEGF, JUN, NFKBIA, PRKCE
  1. Shown are those SuperPaths that were highly significant (P < 0.001)