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Table 3 Pathological characteristics of patients carrying or not BRCA1/2 mutations

From: Clinical and pathological features of BRCA1/2 tumors in a sample of high-risk Moroccan breast cancer patients

Variables BRCA1/2+ BRCA1/2− p value
Histological type
 Invasive ductal carcinoma 10 (90.9 %) 27 (93.1 %) 0.63
 Invasive lobular carcinoma 0 (0 %) 1 (3.4 %)  
 Medullary carcinoma 1 (9.1 %) 1 (3.4 %)  
Tumor size
 T1–T2 8 (72.7 %) 19 (65.5 %) 1.00
 T3 2 (18.2 %) (20.7 %)  
 T4 1 (9.1 %) 4 (13.8 %)  
SBR grade
 I–II 4 (36.4 %) 23 (79.3 %) 0.02
 III 7 (63.6 %) 6 (20.7 %)  
Node involvement
 N− 5 (45.5 %) 13 (44.8 %) 1.00
 N+ 6 (54.5 %) 16 (55.2 %)  
Estrogen receptors status
 ER− 7 (63.6 %) 10 (40.0 %) 0.28
 ER+ 4 (36.4 %) 15 (60.0 %)  
Progesterone receptors status
 PR− 7 (63.6 %) 11 (44.0 %) 0.47
 PR+ 4 (36.4 %) 14 (56.0 %)  
Her2/neu
 Her2− 5 (62.5 %) 16 (66.7 %) 1.00
 Her2+ 3 (37.5 %) 8 (33.3 %)  
Triple negative (ER−, PR− and HER2/neu−)
 Yes 5 (62.5 %) 4 (16.7 %) 0.02
 No 3 (37.5 %) 20 (83.3 %)  
  1. Values in Italic are statistically significant (p value ≤ 0.05)