Skip to main content

Advertisement

Table 4 Inter-observer agreement when determining nerve fiber density in skin biopsies of SFN patients using LDT

From: Automated PGP9.5 immunofluorescence staining: a valuable tool in the assessment of small fiber neuropathy?

  ICC
IENF 0.97
 IENF_Si 0.98
 IENF_Br 0.93
IENF_F 0.99
 IENF_FSi 0.99
 IENF_FBr 0.97
Total ENF 0.99
  1. ENF epidermal nerve fiber GS-EFNS: gold standard method according to EFNS, ICC itra-class correlation, IENF intra-epidermal nerve fiber, IENF_Si intra-epidermal nerve fiber crossing dermal-epidermal junction as single fiber, IENF_Br intra-epidermal nerve fiber crossing dermal-epidermal junction as fiber showing branching, IENF_F ierve fiber fragment lying free in epidermis, IENF_FSi ierve fiber fragment lying free in epidermis as single fragment, IENF_FBr nerve fiber fragment lying free in epidermis showing branching, LDT laboratory developed test, SFN small fiber neuropathy