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Table 4 Minimal inhibitory concentrations (MIC, given in μg/mL) of test lipids that effected a growth inhibition of >95 % against at least two different bacterial strains in the screening assay

From: Assessment of free fatty acids and cholesteryl esters delivered in liposomes as novel class of antibiotic

Liposomal formulationa Bacterial strainb
PA4 0.50 2 NT
SA4 0.25 0.50 NT
LA3 64 NT >64
CL3 1 NT 8
  1. Shown are MIC values derived from two independent experiments each performed in triplicate. NT not tested because not susceptible in the screening assay
  2. aSee Table 1 for letter abbreviations; numbers indicate the type of liposomal formulation used
  3. b SE multidrug-resistant Staphylococcus epidermidis ATCC 700566, VRE vancomycin resistant Enterococcus faecalis ATCC 700802, PACF Pseudomonas aeruginosa, cystic fibrosis isolate