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Table 4 Referral and hazard of repeated poisoning—Cox regression analysis

From: Follow-up of young patients after acute poisoning by substances of abuse: a comparative cohort study at an emergency outpatient clinic

  n Events Crude Adjusted
Hazard ratio 95 % CI p Hazard ratio 95 % CI p
Age
16–22 yearsa 683 50       
23–27 years 437 54 1.7 1.2–2.5 0.005 1.1 0.74–1.7 0.62
Sex         
Femalesa 518 37       
Males 602 67 1.6 1.1–2.4 0.021 1.2 0.76–1.8 0.50
Main toxic agent        
Ethanola 715 27       
Opioids 170 48 9.2 5.7–14.8 <0.001 8.5 5.0–14.3 <0.001
Benzodiazepines 89 12 3.9 2.0–7.7 <0.001 3.8 1.8–7.8 <0.001
Central stimulants 49 6 3.5 1.4–8.5 0.006 3.2 1.3–8.0 0.012
GHB 60 8 3.7 1.7–8.1 0.001 3.4 1.5–7.9 0.004
Other 37 3 2.2 0.66 -7.1 0.20 2.1 0.63–6.9 0.23
Referral to follow-up        
No referrala 709 55       
Referral 411 49 2.0 1.4–2.9 <0.001 1.0 0.69–1.6 0.83
  1. Referral to follow-up and hazard of repetition of poisoning in 1120 patients aged 16–27 years presenting with acute poisoning by substances of abuse in 2008 and 2012
  2. There were 104 events (repetitions). One patient was censored due to death, two were censored due to emigration
  3. The hazard ratio for referrals was hardly affected by entering age and sex into the model, but changed when main toxic agent was entered
  4. aReference group